BASIC FACTS ABOUT ALCOHOL




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lcohol is in the class of depressants. Depressants are substances that inhibit the function of the central nervous system (CNS) by decreasing its activity. Alcohol is a byproduct of an organic compound characterized by carbon chains linked to hydroxyl ions. Ethanol is the main psychoactive component in all alcoholic beverages e.g. beer, whisky, and wine, it is very small in size in comparison with the other molecules with which it interacts within the human body.

Which is more harmful, Beer or Wine?                    

The majority of people’s opinion is that drinking beer has more serious negative health consequences than wine and will shun beer as a harmful alcoholic drink but readily embrace wine as a safer drink. Contrary to this popular belief, wine has a higher alcohol content as compared to beer. Sprits and whisky have the highest level of alcohol content because, while beer and wine are made through fermentation, whiskeys are produced from distillation.


In comparison, beer and wine are similar depending on the amount one takes. Actually, beer, wine, and spirits have the same amount of alcohol content, depending on the amount of alcohol consumed. This concept can be better explained if we consider the understanding of a standard drink.

A standard drink is any drink that contains about 14 grams of pure alcohol, it is equivalent to 1 bottle of beer, for example, Tusker (330 ml) which contains 4.5% alcohol content. This amount is equivalent to a glass of wine (140 ml) which contains 12% alcohol content, which in turn is equivalent to a shot of Whisky, let’s say Jack Daniels (40 ml) which contains 40% alcohol content. In this concept of a standard drink, 1 bottle of wine (750 ml) is equivalent to 5 bottles of Tusker (330 ml), while 1 bottle of whiskey (750 ml) contains 18 standard drinks.

Alcohol absorption

Alcohol is absorbed into the bloodstream both from the stomach and duodenum and circulated throughout the entire body. When food is consumed with alcohol, the food dilutes the alcohol concentration in the stomach and delays passage into the duodenum, slowing absorption and decreasing the subjective effects of alcohol. Food delays and lowers peak blood alcohol concentration (BAC) but also lower the total amount of alcohol reaching the systemic circulation.

Alcohol absorption is fastest when the stomach is empty. It distributes rapidly, with concentrations in body water 10 times higher than in body fat. Shortly after alcohol ingestion, the ethanol concentration in the brain is higher than the venous concentration. The kidneys and lungs remove about 10 percent of the alcohol while approximately 5%–10% of alcohol is excreted in the breath and urine.

Alcohol metabolism

The primary route of alcohol metabolism is oxidation to acetaldehyde and acetic acid. The stomach and the small intestines produce an enzyme called alcohol dehydrogenase which helps in the breakdown of alcohol to water and acetate acid. The liver breaks down the rest of the alcohol into acetic acid. Some of the alcohol is converted to other substances such as fat commonly known as in "beer belly”. Some is burned as energy and converted to water and carbon dioxide.

Lower levels of Alcohol Dehydrogenase (ADH) enzyme in women may account for the higher blood alcohol concentrations in women than in men given equivalent amounts of alcohol. This is the reason why a woman will become intoxicated fast compared to a man and also why women are more likely to develop alcohol addiction as compared to men.


Drinking Patterns

Based on these scientific realities WHO has developed patterns of drinking that helps in preventing negative health consequences to the consumer:

  •  Low risk drinking: Not more than 4 drinks or 3 drinks per day or not more than 14 drinks per week
  • At risk drinking: More than 4 drinks per day
  • Binge: heavy episodic consumption of more than 4 drinks in women and more than 5 drinks per occasion for men or more than 5 drinks per occasion at least once in the past 30 days or a pattern of drinking alcohol that brings Blood Alcohol Concentration (BAC) level to 0.8 + in 2 hours.

Alcohol consumption occurs along a continuum, and drinking patterns vary considerably among individuals, with no clear demarcation between “social” or “moderate” drinking and “problem” or “harmful” drinking.

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